N-[(1,1-Dimethylethoxy)carbonyl]-D-aspartic acid 1-(tert-butyl) ester - Names and Identifiers
N-[(1,1-Dimethylethoxy)carbonyl]-D-aspartic acid 1-(tert-butyl) ester - Physico-chemical Properties
Molecular Formula | C13H23NO6
|
Molar Mass | 289.32 |
Density | 1.139 |
Boling Point | 429.0±40.0 °C(Predicted) |
Appearance | Solid |
pKa | 4.13±0.19(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
N-[(1,1-Dimethylethoxy)carbonyl]-D-aspartic acid 1-(tert-butyl) ester - Introduction
Boc-D-Asp-OtBu(Boc-D-Asp-OtBu) is an organic compound. Its properties are as follows:
1. Appearance: white or almost white crystal.
2. molecular formula: C16H23BrN2O6.
3. Molecular weight: 426.27g/mol.
Boc-D-Asp-OtBu are mainly used for peptide synthesis in biomedical research and drug synthesis. It is used as a derivative of protected amino acids to prevent other reactions during the synthesis and to protect functional groups such as carboxylic acids and amino groups.
The preparation Boc-D-Asp-OtBu usually has the following steps:
1. Reaction of D-5-bromouracil with di (t-butoxycarbonyl) succinate to give Boc-D-Asp-OtBu.
2. react Boc-D-Asp-OtBu with copper sulfate to remove butyl protecting group and generate Boc-D-Asp-OtBu.
When using the Boc-D-Asp-OtBu, you need to pay attention to the following safety information:
1. Boc-D-Asp-OtBu is a chemical that needs to be used and stored correctly in the laboratory.
2. Inhalation, swallowing and contact with skin and eyes must be avoided.
3. Wear appropriate personal protective equipment, such as gloves and safety glasses, when using the Boc-D-Asp-OtBu.
4. Need to operate in a well-ventilated place to avoid harmful gases.
5. Observe local regulations and safe practices when handling and disposing of waste.
In general, Boc-D-Asp-OtBu is a protecting group compound commonly used in organic synthesis and biomedical research, but it is necessary to pay attention to safe operation when using it.
Last Update:2024-04-09 21:21:28